Life emerged and remains an RNA world. All types of cellular RNA undergo post-transcriptional modification either through chemical modification, base-editing or non-templated nucleotide additions. Recent work has demonstrated that post-transcriptional modification of the transcriptome is highly dynamic and important for normal physiology and often de-regulated in disease. Post-transcriptional modification affects utilisation, stability, structure and interactions of cellular RNA. Mutations in enzymes and proteins regulating RNA modification are mutated in many human diseases. This international conference is focused on this emerging new field of “RNA epigenetics”. We will cover all aspects of this emerging topic, from methods development to molecular mechanisms, from disease association to therapeutic starting points. This meeting will be the first of a series that we are organising to focus on this new and exciting area of science. It will be held at St Catharine’s, a historic college in the heart of the city of Cambridge.
Confirmed Speakers
The RNA epigenetics in human disease 2019 conference, supported by STORM Therapeutics, features an incredible line up of speakers covering aspects of RNA epigenetics: biological function, chemistry, technology development and human disease and provides an opportunity to engage with pioneers in RNA epigenetics and present your own work.
Herchel Smith Professor of Medicinal Chemistry – University of Cambridge
Professor for Chemistry – LMU Munich
President, Chief Scientific Officer & Co-founder – Accent Therapeutics, Inc
Valérie de Crécy-Lagard
University of Florida
Michaela Fry
Principal Investigator – German Cancer Research Center – DKFZ
Francois Fuks
Université Libre de Bruxelles Cancer Research Center
Richard Gregory
Principal Investigator – Boston Children’s Hospital
Chuan He
Professor – The University of Chicago
Stacy Horner
Assistant Professor – Duke University Medical Center
Samie Jaffrey
Professor – Weill Medical College, Cornell University
Narry Kim
Institute for Basic Science and Seoul National University
Tony Kouzarides
Gurdon Institute and STORM Therapeutics
Kamil Kranc
Barts Cancer Institute, Queen Mary University of London
Jeannie Lee
Harvard Medical School
Michal Minczuk
MRC Mitochondrial Biology Unit
Eric Miska
Gurdon Institute and STORM Therapeutics
Gerhard Müller
Chief Scientific Officer – Gotham Therapeutics
Yunsun Nam
Assistant Professor – Cecil H and Ida Green Center for Reproductive Biology Sciences
Oliver Rausch
Chief Scientific Officer – STORM Therapeutics
Gidi Rechavi
Head – Sheba Cancer Research Center
Schraga Schwartz
Weizmann Institute of Science
Tom Suzuki
Professor – University of Tokyo
Topics
Molecular and cellular mechanisms | New methods and technologies | Disease association | Therapeutic starting points |
---|---|---|---|
RNA modifications in control of transcription | Mass Spectrometry | Cancer |
Academia & Biotech |
RNA modifications in control of translation | Sequencing | Human genetic disorders | |
RNA modification and RNA metabolism | Infectious disease |